• Animated Atlas of Neuropathic Pain

The Animated Atlas of Neuropathic Pain is a comprehensive collection of 36 animated videos and around 60 images pertaining to the perception and transmission of pain to the brain via the nociceptors and nerves, the physiology of pain transmission, biological molecules that regulate sensation of pain, types of neuropathic pain, and their treatment using drug therapy or nerve stimulation. The Animated Atlas is an excellent reference and an invaluable resource for effective presentations and lectures.


Table of contetns:

Neurobiology of pain

Neurotransmitters – Peptides, excitatory amino acids, nitric oxide.... Peripheral pain mediators.... Prostaglandin E2 (PGE2) as CNS and bradykinin as peripheral pain mediators or modulators.... Substance P and feed-forward inhibition.... Cellular and molecular mechanisms of pain.... Chemokines as pain mediators and modulators.... Neurotrophins: mediators and modulators of pain.... Immune and glial cell factors as pain mediators and modulators.... Pro-inflammatory cytokines.... Role of non-neuronal cell factors.... Glial activation.... Neuroanatomy of pain perception - the supraspinal network & noxious sensory stimuli.... Pain pathways – ascending & descending pathways; Gate control.... Plasticity of pain-related neuronal activity in the thalamus; role of the dorsal horn.... The genetics of pain.... Autonomic-endocrine-immune interactions in acute and chronic pain.... Placebo analgesia

Neuropathic Pain

Peripheral nerve injury and neuropathic pain.... Neuronal (including brain imaging) and molecular mechanisms in neuropathic pain.... Phantom limb pain.... Postherpetic neuralgia.... Diabetic neuropathy.... Allodynia.... Hyperpathia.... Neurotrophic factors.... Role of sodium channels.... Changes in hypothalamo-pituitary-adrenal (HPA) axis.... Role of microglial cell in the pathogenesis of neuropathic pain.... Ectopic nerve impulse generation.... Neurotrophic factor treatment for neuropathic pain.... Ectopic nerve impulse suppression – role of gabapentin.... Anticonvulsants for neuropathic pain.... Tricyclic antidepressants.... Stimulation - Spinal cord and brain stimulation... Implantable intrathecal drug delivery systems.... Sodium channel blockers

Animated Atlas of Neuropathic Pain


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