Osteoarthritis, the most common form of arthritis strongly associated with aging, is a disease that is characterized by focal, discrete areas of degradation of the cartilage surfaces of the joints. The Animated Atlas of Osteoarthritis is a comprehensive collection of animated videos pertaining to the anatomy of joints, cartilage composition and function, types of osteoarthritis, its pathophysiology, biological causes and risk factors, diagnosis and treatment options including medications and/or surgical methods.
Table of contents
1. Anatomy of Joint, Types, Pathophysiology & Symptoms of Osteoarthritis
1. Anatomy of normal joints
2. Composition of the cartilage
3. Joints in osteoarthritis
4. Collagen network
5. Symptoms of osteoarthritis
6. Types of osteoarthritis
7. Subchondral cysts
8. Progressive cartilage destruction
9. Phases of osteoarthritis progression
10. Hip osteoarthritis
11. Spinal osteoarthritis
12. Knee osteoarthritis
13. Bone spurs or osteophytes
14. Heberden's and Bouchard's nodes
15. Bunions associated with osteoarthritis
16. Cartilage metabolism in osteoarthritis
17. Pathophysiology of osteoarthritis pain
2. Causes & Risk Factors for Osteoarthritis
1. Thyroidism leading to osteoarthritis
2. Paget's disease and osteoarthritis
3. Bone mineral density and osteoarthritis
4. Role of metalloproteinases in cartilage damage
5. Obesity and osteoarthritis
6. Influence of IGF-1 on cartilage matrix proteins
7. Trauma as a factor for osteoarthritis
8. Uric acid in osteoarthritis
9. Calcium pyrophosphate in osteoarthritis
10. Congenital abnormalities that lead to osteoarthritis
11. Proteoglycan loss in osteoarthritis
12. Increased water content during osteoarthritis
13. Role of proteolytic enzymes in matrix degradation
14. Cathepsins in osteoarthritis
15. Osteoarthritis at menopause
16. Genes involved in osteoarthritis
17. Osteoarthritis following meniscectomy
18. Smoking and cartilage loss in knee osteoarthritis
19. Interleukins in cartilage damage
20. Role of TNF-α in cartilage degeneration
21. Nitric oxide in osteoarthritis
22. Cyclooxygenase activity in osteoarthritis
3. Diagnosis & Treatment of Osteoarthritis
1. X-ray to detect osteoarthritis
2. MRI in the diagnosis of osteoarthritis
3. Biological markers to diagnose osteoarthritis
4. Arthrocentesis
5. Arthroscopy
6. Anti-inflammatory drugs for osteoarthritis
7. COX-2 inhibitors
8. Glucosamine and chondroitin supplements to treat osteoarthritis
9. Osteotomy
10. Total joint replacement
11. Arthrodesis
12. Arthroplasty
13. Blocking tumor necrosis factor
14. Chondroplasty
15. Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis
16. Blocking tumor necrosis factor
17. Hyaluronic acid injections for joint health in osteoarthritis