The Animated Atlas of Diabetes is a comprehensive collection of animated videos that explore glucose metabolism, the action of insulin in glucose uptake, and diabetes. It delves into the biological factors contributing to the onset of diabetes, its complications, and management strategies.
Table of contents
1. Insulin, glucose metabolism and diabetes
1. Anatomy of pancreas
2. Beta cell function
3. Glucose transport proteins
4. Diabetes
5. Insulin
6. Insulin gene expression
7. Mature beta granule storage pool
8. Movement of secretory granules to the plasma membrane and exocytosis
9. Role of C-peptide in the synthesis of insulin
10. Insulin
11. Insulin receptor structure and function
12. Regulation of insulin receptor expression
13. Insulin like growth factors
14. Insulin signalling pathways
15. Regulation of proinsulin conversion
16. Proteolytic enzymes involved in proinsulin conversion
17. Inefficient conversion of proinsulin to insulin
18. Dysfunctional proinsulin processing in diabetes
19. Insulin-mediated regulation of glucose metabolism
20. Role of beta cell in glucose homeostasis
21. Role of hypothalamus in peripheral glucose metabolism
22. Incretins
23. GLP-1 (glucagon like peptide-1) secretion, metabolism and clearance
24. GLP-1 receptor
25. Leptin
26. Gastrin releasing polypeptide
2. Biological factors in diabetes
1. NEFA (nonesterified fatty acids) signalling
2. Role of NEFAs in insulin resistance
3. Genetic factors (melanocortin-4 receptor, leptin receptor, prohormone convertase 1)
4. Polymorphisms of the insulin gene
5. Antibodies directed against islet cells
6. Immunity directed against beta cells
7. IA-2 (ICA512) and IA-2β (phogrin)-membrane-associated autoantigen
8. Anti-insulin antibody-mediated insulin resistance
9. CRABP-1 (cellular retinoic acid binding protein-1) and insulin resistance
10. Role of IL-6 (interleukin-6) and insulin resistance
11. Tumor Necrosis Factor-α and insulin resistance
12. Insulin resistance and type 2 diabetes
13. C-peptide and Type 2 diabete
14. The functional basis for HLA class II association with type I diabetes
15. Pathophysiology of maturity onset diabetes of the young type 2 (MODY 2)
3. Diabetes - complications and management
1. Diabetes secondary to pancreatitis
2. Obesity and insulin resistance
3. Mitochondrial diabetes
4. Gestational diabetes mellitus
5. Diabetic foot
6. Gangrene and diabetes
7. Retinopathy
8. Diabetic nephropathy
9. Diabetic ketoacidosis
10. Mechanism of metformin for the anithyperglycemic effect
11. Site of primary action of oral sulfonylureas
12. α-Glucosidase inhibitors in the treatment of hyperglycemia
13. Use of thiazolidinediones to decrease peripheral insulin resistance
14. Use of meglitinides in the treatment of type 2 diabetes
15. Different types of Insulin for treating diabetes