1. Neurobiology of pain

1. Neurotransmitters - Peptides, excitatory amino acids, nitric oxide
2. Peripheral pain mediators
3. Prostaglandin E2 (PGE2) as CNS and bradykinin as peripheral pain mediators or modulators
4. Substance P and feed-forward inhibition
5. Cellular and molecular mechanisms of pain
6. Chemokines as pain mediators and modulators
7. Neurotrophins: mediators and modulators of pain
8. Immune and glial cell factors as pain mediators and modulators
9. Pro-inflammatory cytokines
10. Role of non-neuronal cell factors
11. Glial activation
12. Neuroanatomy of pain perception - the supraspinal network & noxious sensory stimuli
13. Pain pathways - ascending & descending pathways; Gate control
14. Plasticity of pain-related neuronal activity in the thalamus; role of the dorsal horn
15. The genetics of pain
16. Autonomic-endocrine-immune interactions in acute and chronic pain
17. Placebo analgesia

← Neuropathic Pain

1. Neurotransmitters - Peptides, excitatory amino acids, nitric oxide