The Animated Atlas of Diabetes is a comprehensive collection of 63 animated videos and around 120 images pertaining to glucose metabolism, action of insulin in glucose uptake, diabetes, biological factors playing a role in the onset of diabetes, its complications and management. The Animated Atlas is an excellent reference and an invaluable resource for effective presentations and lectures.


Table of contents:

Insulin, glucose metabolism and diabetes

Anatomy of pancreas.... Beta cell function.... Glucose transport proteins.... Diabetes .... Insulin.... Insulin gene expression .... Mature beta granule storage pool .... Movement of secretory granules to the plasma membrane and exocytosis.... Role of C-peptide in the synthesis of.... insulin.... Insulin receptor structure and function.... Regulation of insulin receptor expression.... Insulin like growth factors.... Insulin signalling pathways.... Regulation of proinsulin conversion.... Proteolytic enzymes involved in.... proinsulin conversion.... Inefficient conversion of proinsulin to insulin.... Dysfunctional proinsulin processing in diabetes.... Insulin-mediated regulation of glucose metabolism.... Role of beta cell in glucose homeostasis.... Role of hypothalamus in peripheral glucose metabolism.... Incretins.... GLP-1 (glucagon like peptide-1) secretion, metabolism and clearance.... GLP-1 receptor.... Leptin.... Gastrin releasing polypeptide....

Biological factors in diabetes

NEFA (nonesterified fatty acids )signalling.... Role of NEFAs in insulin resistance.... Genetic factors (melanocortin-4 receptor, leptin receptor, prohormone convertase 1).... Polymorphisms of the insulin gene.... Antibodies directed against islet cells.... Immunity directed against beta cells.... IA-2 (ICA512) and IA-2β (phogrin)-membrane-associated autoantigen.... Anti-insulin antibody-mediated insulin resistance.... CRABP-1 (cellular retinoic acid binding protein-1) and insulin resistance.... Role of IL-6 (interleukin-6) and insulin resistance.... Tumour Necrosis Factor-α and insulin resistance.... Insulin resistance and type 2 diabetes.... C-peptide and Type 2 diabetes.... The functional basis for HLA class II association with type I diabetes.... Pathophysiology of maturity onset diabetes of the young type 2 (MODY 2)....

Diabetes – complications and management

Diabetes secondary to pancreatitis.... Obesity and insulin resistance.... Mitochondrial diabetes.... Gestational diabetes mellitus.... Diabetic foot.... Gangrene and diabetes.... Retinopathy.... Diabetic nephropathy.... Diabetic ketoacidosis.... Mechanism of metformin for the anithyperglycemic effect.... Site of primary action of oral sulfonylureas.... α-Glucosidase inhibitors in the treatment of hyperglycemia.... Use of thiazolidinediones to decrease peripheral insulin resistance.... Use of meglitinides in the treatment of type 2 diabetes.... Different types of Insulin for treating diabetes.... Insulin pump therapy.... Role of DPP-4 (dipeptidyl peptidase-4) inhibitors in the ent of diabetes or incretin-enhancing DPP4-inhibitors.... Synthetic recombinant exendin-4 (exenatide).... Islet amyloid polypeptide (IAPP) therapy).... Role of PPAR-γ ligands (TZDS) in treating type 2 diabetes).... Gastric surgery in type 2 diabetes).... New drugs for the treatment of diabetes mellitus).... Diabetes treatment targeting brain (resveratrol-sirtuins in brain))....


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Animated Atlas of Diabetes


Tags: Diabetes